Molecular

Mechanism of action of afatinib

Mechanism of action of afatinib
Mechanism of action of afatinib. By Anypodetos, CC0, via Wikimedia Commons.

Description

A reaction scheme showing how the cancer drug afatinib attaches permanently to the epidermal growth factor receptor (EGFR). The drug forms a covalent bond with cysteine 797 of the receptor through a Michael addition.

This illustration was created by Anypodetos and is not Sterling IMRES work. It is shown under CC0. Reuse it only on the terms of that licence and credit the creator.

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