Division

Pharmacology and Natural Products Division

The Pharmacology and Natural Products Division studies how medicines act and how they are used safely. Its scope includes therapeutics, medication safety and the evaluation of natural products as sources of new drugs.

8publications
2books
4registered studies
88credited people
Overview and scope

Key subject areas

Pharmacology, therapeutics, natural products and medication-related research.

Clinical pharmacology

Therapeutics

Natural product drug discovery

Pharmacovigilance and medication safety

Ethnopharmacology

Antimicrobial stewardship

Staff and contributors

People

Verified Sterling IMRES staff will be listed here. Until then, these are the people credited on this division’s library works (not institute staff).

All people in this division
Active research

Registered studies

Research hub
UpcomingInterventionalPhase 1

A Clinical Study of Piperaquine, Pyronaridine, and Artesunate Administered in Combination in Healthy Adults

University of Oxford

This University of Oxford Phase 1 study in Thailand will give healthy adult volunteers three regimens in randomised sequence: piperaquine alone, pyronaridine-artesunate alone, and all three drugs together. Each course runs for three days with follow-up and washout periods between regimens. The aim is to understand how the drugs interact before wider use of triple artemisinin-based combinations.

2026
RecruitingInterventionalPhase 1 / Phase 2

Curcumin and Retinal Study

Texas Tech University Health Sciences Center

This small randomised study at Texas Tech University Health Sciences Center gives participants either a low or a high dose of curcumin for two weeks. Retinal imaging is used to see whether curcumin crosses into nervous tissue and attaches to amyloid proteins. Researchers also look at safety, blood levels and gut bacteria.

2023

Completed and published

PublishedInterventional

Systolic Blood Pressure Intervention Trial

National Heart, Lung, and Blood Institute (NHLBI)

SPRINT was a large US multicentre randomised trial run by the NHLBI that compared two blood pressure targets in adults with hypertension. Participants were assigned either to an intensive systolic target or to the conventional target, and were followed for major cardiovascular events. Its main findings were published in the New England Journal of Medicine in 2015.

2010
PublishedInterventionalPhase 3

Longitudinal Antimalarial Combinations in Uganda

University of California, San Francisco

This Phase 3 study followed a cohort of young children in Kampala, Uganda, treating each malaria episode with one of three randomised drug combinations: amodiaquine plus artesunate, amodiaquine plus sulfadoxine-pyrimethamine, or artemether-lumefantrine. Following children over time allowed comparison of efficacy and safety across repeated treatments. Several results papers are linked in the registry.

2004
Publications and books

Reference library

All publications

Books

Textbook

Rang & Dale's Pharmacology

James M. Ritter, Rod J. Flower, Graeme Henderson et al.

10th editionElsevier2023
Visual resources

Illustrations

Gallery
Educational activities

Planned teaching

Focus areas: Principles of pharmacology, Medication safety, Evaluating natural product evidence.

Education
Upcomingcourse

Biomedical foundations for clinical learners

For: Students in medicine, dentistry, nursing and allied health

Physiology, pathology and pharmacology principles linked to clinical reasoning through illustrated cases.

  • Explain core physiological control systems
  • Link mechanisms of disease to presentation
  • Relate drug action to mechanism
Not yet enrolling · no accredited award

Collaborate with the Pharmacology division

Opportunities: Natural product and pharmacology research; Medication safety reviews; Pharmacology teaching resources.