Research articleOpen access

Dapagliflozin in Patients with Heart Failure and Reduced Ejection Fraction

New England Journal of Medicine · 21 November 2019

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Summary

Reports the DAPA-HF trial of dapagliflozin added to standard therapy in patients with heart failure and reduced ejection fraction, with and without diabetes. The trial established SGLT2 inhibition as a treatment for heart failure in its own right and is a cornerstone of current heart-failure care.

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Authors

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Cite this work

McMurray JJ, Solomon SD, Inzucchi SE, Køber L, Kosiborod MN, Martinez FA, et al. Dapagliflozin in Patients with Heart Failure and Reduced Ejection Fraction. New England Journal of Medicine. 2019;381(21):1995-2008. doi:10.1056/NEJMoa1911303

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