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Hallmarks of aging: An expanding universe

Cell · January 2023

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Summary

A revision of the 2013 hallmarks of aging framework that expands the list of interconnected molecular and cellular processes driving ageing, adding hallmarks such as disabled macroautophagy, chronic inflammation and dysbiosis. It serves as a reference map for studying ageing biology and age-related disease.

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López-Otín C, Blasco MA, Partridge L, Serrano M, Kroemer G. Hallmarks of aging: An expanding universe. Cell. 2023;186(2):243-278. doi:10.1016/j.cell.2022.11.001

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