Sterling IMRES
Sign in
Educational articleOpen access

Calculating the sample size required for developing a clinical prediction model

BMJ · 18 March 2020

Read at the publisher
Reference library record. This work was written and published by the people and publisher named here. It is listed in the Sterling IMRES reference library for study and citation. Sterling IMRES did not author or publish it, and listing a work does not mean its authors are affiliated with the institute. Metadata verified via Crossref. How records are verified

Summary

A practical guide to calculating the minimum sample size needed when developing a clinical prediction model, with criteria for binary, time-to-event and continuous outcomes. It addresses the frequent problem of models built on too little data and points readers to software that implements the calculations.

Summary written by Sterling IMRES editors. Read the original abstract at the publisher.

Authors

Cite this work

Riley RD, Ensor J, Snell KIE, Harrell FE, Martin GP, Reitsma JB, et al. Calculating the sample size required for developing a clinical prediction model. BMJ. 2020;368:m441. doi:10.1136/bmj.m441

Related publications