Natural Products as Sources of New Drugs over the Nearly Four Decades from 01/1981 to 09/2019OPEN ACCESS
Journal of Natural Products · DOI: 10.1021/acs.jnatprod.9b01285
Nature Reviews Drug Discovery · 28 January 2021
A wide-ranging review by an international taskforce on how natural products are being brought back into drug discovery. It discusses technical advances such as improved analytical tools, genome mining and engineering, and microbial culturing that help overcome historical barriers, and points to opportunities including new antimicrobials.
Summary written by Sterling IMRES editors. Read the original abstract at the publisher.
Group author: the International Natural Product Sciences Taskforce. The full author list is available from the publisher.
Atanasov AG, Zotchev SB, Dirsch VM, Orhan IE, Banach M, Rollinger JM, et al. Natural products in drug discovery: advances and opportunities. Nature Reviews Drug Discovery. 2021;20(3):200-216. doi:10.1038/s41573-020-00114-z
Journal of Natural Products · DOI: 10.1021/acs.jnatprod.9b01285
Biotechnology Advances · DOI: 10.1016/j.biotechadv.2015.08.001