Natural products in drug discovery: advances and opportunitiesOPEN ACCESS
Nature Reviews Drug Discovery · DOI: 10.1038/s41573-020-00114-z
Biotechnology Advances · December 2015
A review of how pharmacologically active compounds are discovered in plants, covering ethnopharmacology-guided selection, screening strategies and analytical methods. It also addresses the practical problem of securing enough material for development, discussing options such as cultivation, synthesis and biotechnological production.
Summary written by Sterling IMRES editors. Read the original abstract at the publisher.
The full author list is available from the publisher.
Atanasov AG, Waltenberger B, Pferschy-Wenzig EM, Linder T, Wawrosch C, Uhrin P, et al. Discovery and resupply of pharmacologically active plant-derived natural products: A review. Biotechnology Advances. 2015;33(8):1582-1614. doi:10.1016/j.biotechadv.2015.08.001
Nature Reviews Drug Discovery · DOI: 10.1038/s41573-020-00114-z
Journal of Natural Products · DOI: 10.1021/acs.jnatprod.9b01285