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Clinical reviewOpen access

Reducing Inappropriate Polypharmacy: The Process of Deprescribing

JAMA Internal Medicine · 1 May 2015

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Summary

A clinical review that sets out a structured, patient-centred process for deprescribing, meaning the supervised withdrawal of medicines whose harms may outweigh their benefits. It is widely used as a practical framework for reducing inappropriate polypharmacy, especially in older people taking many medicines.

Summary written by Sterling IMRES editors. Read the original abstract at the publisher.

Authors

  • Ian A. ScottDepartment of Internal Medicine and Clinical Epidemiology, Princess Alexandra Hospital, Brisbane, Australia2School of Medicine, University of Queensland, Brisbane, Australia
  • Sarah N. HilmerDepartment of Clinical Pharmacology, Royal North Shore Hospital, Sydney, Australia4Kolling Institute of Medical Research, School of Medicine, University of Sydney, Sydney, Australia
  • Emily ReeveKolling Institute of Medical Research, School of Medicine, University of Sydney, Sydney, Australia5Cognitive Decline Partnership Centre, School of Medicine, University of Sydney, Sydney Australia
  • Kathleen PotterWestern Australia Centre for Health and Aging, Perth, Australia
  • David Le CouteurAgeing and Alzheimers Institute, Concord Hospital and Sydney Research, University of Sydney, Sydney, Australia
  • Deborah RigbyNational Prescribing Service MedicineWise, School of Pharmacy, University of Queensland, Brisbane, Australia9School of Pharmaceutical Sciences,Queensland University of Technology, Brisbane, Australia
  • Danijela GnjidicSchool of Pharmacy, University of Sydney, Sydney, Australia
  • Christopher B. Del MarCentre for Research in Evidence-based Practice, Bond University, Gold Coast, Australia
  • Elizabeth E. RougheadSchool of Pharmacy and Medical Sciences, University of South Australia, Adelaide, Australia
  • Amy PageSchool of Medicine and Pharmacology, University of Western Australia, Perth, Australia
  • Jesse JansenScreening and Test Evaluation Program (STEP), Sydney School of Public Health, Centre for Medical Psychology and Evidence-based Decision-making (CeMPED), University of Sydney, Sydney, Australia
  • Jennifer H. MartinPA-Southside Clinical School, University of Queensland, Brisbane, Australia

Cite this work

Scott IA, Hilmer SN, Reeve E, Potter K, Couteur DL, Rigby D, et al. Reducing Inappropriate Polypharmacy: The Process of Deprescribing. JAMA Internal Medicine. 2015;175(5):827. doi:10.1001/jamainternmed.2015.0324

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