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In progressInterventional

Periodontitis Treatment and Heart Failure

Effects Of PeriodontitisTtreatment On The Worsening Of Heart Failure: A Randomized Clinical Trial

This is a registered study tracked in the Sterling IMRES research watch. It is sponsored by University of Taubate and run by the investigators named in the registry, not by Sterling IMRES. Details come from ClinicalTrials.gov, last updated 13 February 2026.

Summary

This Brazilian study treats periodontitis with scaling and root planing in adults with and without heart failure, alongside a delayed-treatment control group. Researchers follow a cardiac marker (NT-proBNP) and oral and immune measures at three and six months. It explores whether gum treatment could have a measurable effect on heart failure.

Objectives

  • Measure whether scaling and root planing changes blood NT-proBNP levels in people with periodontitis and heart failure.
  • Examine links between blood and saliva markers and heart failure severity, and track the immune response to a key oral bacterium.

Methodology

Study design
Randomized, parallel assignment, double-blind, primary purpose: treatment
Conditions
Heart Failure; Periodontitis
Interventions
Mechanical Treatment (procedure)
Primary outcome
NT-proBNP in blood samples
Sample size
80 participants (actual)
Locations
Brazil

Team

0

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